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Research Forming the Scientific Basis of VR-TheraFix

Sensory Experiences

  1. Ulrich, R. S., et al. (1991). Stress recovery during exposure to natural environments. Journal of Environmental Psychology.

    https://psych.utah.edu/_resources/documents/psych4130/Ulrich%20et%20al_1991.pdf.
     

  2. Kaplan, S. (1995). The restorative benefits of nature: Toward an integrative framework (Attention Restoration Theory).

    https://www.centreforecotherapy.org.uk/wp-content/uploads/2021/07/Centre_for_Ecotherapy-the_restorative_benefits_of_nature__kaplan_1995_.pdf.
     

  3. Grupe, D. W., & Nitschke, J. B. (2013). Uncertainty and anticipation in anxiety: an integrated neurobiological and psychological perspective. Nature Reviews Neuroscience.

    https://www.psychiatry.wisc.edu/courses/Nitschke/seminar/Grupe%20%26%20Nitschke%202013%20NRN.pdf.
     

  4. Thayer, J. F., & Lane, R. D. (2000). A model of neurovisceral integration in emotion regulation.

    https://pubmed.ncbi.nlm.nih.gov/19424767/.
     

  5. Shaffer, F., & Ginsberg, J. P. (2017). An overview of heart rate variability metrics and norms. Frontiers in Public Health.

    https://public-pages-files-2025.frontiersin.org/journals/public-health/articles/10.3389/fpubh.2017.00258/pdf.
     

  6. Friston, K., & Kiebel, S. (2009). Predictive coding under the free-energy principle.

    https://www.fil.ion.ucl.ac.uk/~karl/Predictive%20coding%20under%20the%20free-energy%20principle.pdf.
     

  7. 7. Research on the Effects of Visual Environments and EEG Activity (Examples) A series of research studies has demonstrated a relationship between visual characteristics (such as color, contrast, and movement) and changes in EEG measures (including alpha and beta activity), as well as cortical arousal levels. These findings support the hypothesis that an appropriate visual environment may contribute to reducing physiological arousal:

    https://onlinelibrary.wiley.com/doi/full/10.1111/psyp.14438.

 1.  D. M. Torta Torta, D. M., et al. (2017). Attention to pain! A neurocognitive perspective on attentional modulation of pain.

 https://pubmed.ncbi.nlm.nih.gov/28284849/

 

2. J. A. Hoag Hoag, J. A., et al. (2022). Distracting Through Procedural Pain and Distress: RCT of Guided Imagery vs. Comparator.

 https://pubmed.ncbi.nlm.nih.gov/35436209/

 

3. S. F. M. Pizzoli Pizzoli, S. F. M., et al. (2021). A systematic review & meta-analysis of HRV biofeedback.

https://pmc.ncbi.nlm.nih.gov/articles/PMC7988005/

 

4. T. Castro Ribeiro Castro Ribeiro, T., et al. (2023). Assessing effectiveness of HRV-biofeedback protocols.

קישור: https://www.frontiersin.org/articles/10.3389/fphys.2023.1147260/full

 

 

.5 A. S. A. Ashour Ashour, A. S. A., et al. (2022). Is music intervention effective in reducing anxiety and pain during breast biopsy? A systematic review & meta-analysis. Support Care Cancer.

 https://pubmed.ncbi.nlm.nih.gov/36525033/

 

6. M. de Witte de Witte, M., et al. (2020). Effects of music interventions on stress-related outcomes: systematic review & meta-analyses.

 https://www.tandfonline.com/doi/full/10.1080/17437199.2019.1627897tandfonline.com

7. R. McCahill McCahill, R., et al. (2023). Adult pain and anticipatory anxiety assessment in the emergency department: an integrative review.

 https://pubmed.ncbi.nlm.nih.gov/36221311/

 

 

8. T. Kearton Kearton, T., et al. (2020). The influence of predictability and controllability on stress responses. Frontiers in Veterinary Science.

קישור: https://pmc.ncbi.nlm.nih.gov/articles/PMC7733987/

 

9. D. L. Bennett Bennett, D. L., et al. (2020). Music during image-guided breast biopsy reduces pre-procedural anxiety.

 https://pubmed.ncbi.nlm.nih.gov/32353714/

 

10. E. A. Pinto Pinto, E. A., et al. (2023). Modulation of attention to pain by goal-directed action. PeerJ.

 https://peerj.com/articles/16544/peerj.com

1.• Grupe DW, Nitschke JB (2013). Uncertainty and anticipation in

anxiety. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4276319/

 

2.• Chalmers JA et al. (2014). Anxiety disorders are associated with reduced heart rate variability. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4092363/

 

3.• Peerdeman KJ et al. (2016). An integrative review of the influence of expectancies on pain. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4993782/

4.• Atlas LY, Wager TD (2012). How expectations shape pain. https://www.researchgate.net/publication/223993600_How_expectations_shape_pain

5. • Mogg K, Bradley BP (2016). Anxiety and attention to threat. https://www.sciencedirect.com/science/article/pii/S0005796716301310

6. • Zhang H et al. (2015). Modulation of executive attention by threat stimulus. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4589644/

7. • Steenen SA et al. (2024). Interventions to reduce adult state anxiety in dental settings. 

https://www.sciencedirect.com/science/article/pii/S0887618524000677

8. •  Preoperative anxiety and its impact on surgical outcomes.

  https://www.researchgate.net/publication/388916209_Preoperative_anxiety_and_its_impact_on_surgical_outcomes_A_systematic_review_and_meta-analysis

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